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It was important to note that reduction in body weight did not appear to reach a plateau at the end of the treatment and all significant reduction in weight from baseline was seen in all groups administered cagrilintide, in comparison to the placebo group

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That targeted interaction drives its core effects: Cardiolipin stabilization: By binding cardiolipin, SS31 preserves the structural integrity of the mitochondrial inner membrane, maintaining the cristae architecture that the electron transport chain depends on for efficient ATP production